The effects of diuretics on quality of life of hypertensive patients

Esther Paran, O. Anson, L. Neumann

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Objectives: To study the effect of diuretics and diuretics discontinuation on the quality of life (QOL) of hypertensive patients. Methods: 149 beta blocker treated mild to moderate hypertensive patients were included in the study. Seventy-three were treated by beta blockers (BB's) only and 60 by BB's and diuretics, for 40 patients diuretics was discontinued. Physical symptoms and QOL were assessed before and 9-15 months after the change in treatment. Results: At baseline, subjects on diuretics experienced more gastrointestinal symptoms, weakness, and sex related problems; and their QOL was poorer. At the end of the follow-up, patients on diuretics scored poorest on physical strength items and on health perceptions; those who were never treated by diuretics scored best; and those who stopped were in between. Conclusions: Diuretics treatment adversely affect patients' QOL. Cessation of diuretics treatment for at least 9 months improved some aspects of patients' QOL, though those who never received diuretics were better off than others.

Original languageEnglish
Pages (from-to)S147-S152
JournalJournal of Human Hypertension
Issue numberSUPPL. 3
StatePublished - 30 Sep 1996


  • Beta blockers
  • Diuretics
  • Quality of life

ASJC Scopus subject areas

  • Internal Medicine


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