The elicitation, representation, application, and automated discovery of time-oriented declarative clinical knowledge

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

Monitoring, interpretation, and analysis of large amounts of timestamped clinical data are tasks that are at the core of tasks such as the management of chronic patients using clinical guidelines, the retrospective assessment of the quality of that application, or the related task of clinical research by learning new knowledge from the accumulating data. I briefly describe several conceptual and computational architectures developed over the past 20 years, mostly by my research teams at Stanford and Ben Gurion universities, for knowledge-based performance of these tasks, and highlight the complex and interesting relationships amongst them. Examples of such architectures include the IDAN goal-directed temporal-mediation and the Momentum data-driven monitoring architectures, both of which are based on the knowledge-based temporal-abstraction method; the KNAVE-II and VISITORS knowledge-based interactive-exploration frameworks for single and multiple longitudinal records; and the KarmaLego interval-based temporal data mining methodology. I point out the progression from individual-subject datainterpretation, monitoring, and therapy, to multiple-patient aggregate analysis and research, and finally to the discovery and learning of new knowledge. This progression can be viewed as a positive-feedback loop, in which new knowledge is brought back to bear upon both individual-patient management and on the learning of new and meaningful (temporal) associations.

Original languageEnglish
Title of host publicationProcess Support and Knowledge Representation in Health Care - BPM 2012 Joint Workshop, ProHealth 2012/KR4HC 2012, Revised Selected Papers
PublisherSpringer Verlag
Pages1-29
Number of pages29
ISBN (Print)9783642364372
DOIs
StatePublished - 1 Jan 2013
EventBPM 2012 Joint Workshop on 5th Workshop of Process-Oriented Information Systems in Health Care, ProHealth 2012 and 4th Workshop on Knowledge Representation for Health Care, KR4HC 2012 - Tallinn, Estonia
Duration: 3 Sep 20123 Sep 2012

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7738 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

ConferenceBPM 2012 Joint Workshop on 5th Workshop of Process-Oriented Information Systems in Health Care, ProHealth 2012 and 4th Workshop on Knowledge Representation for Health Care, KR4HC 2012
Country/TerritoryEstonia
CityTallinn
Period3/09/123/09/12

Keywords

  • Guideline-based care
  • Information visualization
  • Knowledge acquisition
  • Knowledge representation
  • Medical decision-support systems
  • Temporal abstraction
  • Temporal data mining
  • Temporal reasoning

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