TY - JOUR
T1 - The emergence of metal oxide nanoparticles (NPs) as a phytomedicine
T2 - A two-facet role in plant growth, nano-toxicity and anti-phyto-microbial activity
AU - Bhattacharjee, Rahul
AU - Kumar, Lamha
AU - Mukerjee, Nobendu
AU - Anand, Uttpal
AU - Dhasmana, Archna
AU - Preetam, Subham
AU - Bhaumik, Samudra
AU - Sihi, Sanjana
AU - Pal, Sanjana
AU - Khare, Tushar
AU - Chattopadhyay, Soham
AU - El-Zahaby, Sally A.
AU - Alexiou, Athanasios
AU - Koshy, Eapen P.
AU - Kumar, Vinay
AU - Malik, Sumira
AU - Dey, Abhijit
AU - Proćków, Jarosław
N1 - Funding Information:
Jarosław Proćków received the funds for open access publication fee from the Ministry of Education and Science , Warsaw, Poland.
Publisher Copyright:
© 2022 The Authors
PY - 2022/11/1
Y1 - 2022/11/1
N2 - Anti-microbial resistance (AMR) has recently emerged as an area of high interest owing to the rapid surge of AMR phenotypes. Metal oxide NPs (MeONPs) have been identified as novel phytomedicine and have recently peaked a lot of interest due to their potential applications in combating phytopathogens, besides enhancing plant growth and yields. Numerous MeONPs (Ti2O, MgO, CuO, Ag2O, SiO2, ZnO, and CaO) have been synthesized and tested to validate their antimicrobial roles without causing toxicity to the cells. This review discusses the application of the MeONPs with special emphasis on anti-microbial activities in agriculture and enlists how cellular toxicity caused through reactive oxygen species (ROS) production affects plant growth, morphology, and viability. This review further highlights the two-facet role of silver and copper oxide NPs including their anti-microbial applications and toxicities. Furthermore, the factor modulating nanotoxicity and immunomodulation for cytokine production has also been discussed. Thus, this article will not only provide the researchers with the potential bottlenecks but also emphasizes a comprehensive outline of breakthroughs in the applicability of MeONPs in agriculture.
AB - Anti-microbial resistance (AMR) has recently emerged as an area of high interest owing to the rapid surge of AMR phenotypes. Metal oxide NPs (MeONPs) have been identified as novel phytomedicine and have recently peaked a lot of interest due to their potential applications in combating phytopathogens, besides enhancing plant growth and yields. Numerous MeONPs (Ti2O, MgO, CuO, Ag2O, SiO2, ZnO, and CaO) have been synthesized and tested to validate their antimicrobial roles without causing toxicity to the cells. This review discusses the application of the MeONPs with special emphasis on anti-microbial activities in agriculture and enlists how cellular toxicity caused through reactive oxygen species (ROS) production affects plant growth, morphology, and viability. This review further highlights the two-facet role of silver and copper oxide NPs including their anti-microbial applications and toxicities. Furthermore, the factor modulating nanotoxicity and immunomodulation for cytokine production has also been discussed. Thus, this article will not only provide the researchers with the potential bottlenecks but also emphasizes a comprehensive outline of breakthroughs in the applicability of MeONPs in agriculture.
KW - Anti-bacterial and antifungal activities
KW - Anti-phyto-pathogens activity
KW - Green synthesis
KW - Phyto-nanotechnology
KW - Plant growth and morphology
KW - Therapeutic nanoparticles
UR - http://www.scopus.com/inward/record.url?scp=85138323562&partnerID=8YFLogxK
U2 - 10.1016/j.biopha.2022.113658
DO - 10.1016/j.biopha.2022.113658
M3 - Review article
C2 - 36162370
AN - SCOPUS:85138323562
VL - 155
JO - Biomedicine and Pharmacotherapy
JF - Biomedicine and Pharmacotherapy
SN - 0753-3322
M1 - 113658
ER -