The evolution of embryo implantation

Michael R. McGowen, Offer Erez, Roberto Romero, Derek E. Wildman

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Embryo implantation varies widely in placental mammals. We review this variation in mammals with a special focus on two features: the depth of implantation and embryonic diapause. We discuss the two major types of implantation depth, superficial and interstitial, and map this character on a well-resolved molecular phylogenetic tree of placental mammals. We infer that relatively deep interstitial implantation has independently evolved at least eight times within pla-cental mammals. Moreover, the superficial type of implantation represents the ancestral state for placental mammals. In addition, we review the genes involved in various phases of implantation, and suggest a future direction in investigating the molecular evolution of implantation-related genes.

Original languageEnglish
Pages (from-to)155-161
Number of pages7
JournalInternational Journal of Developmental Biology
Volume58
Issue number2-4
DOIs
StatePublished - 1 Jan 2014
Externally publishedYes

Keywords

  • Gene
  • Implantation
  • Interstitial
  • Mammal
  • Phylogeny
  • Superficial

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