The genome of plasmodium falciparum. I: DNA base composition

Yaakov Pollack, Alisa L. Katzen, Dan T. Spira, Jacob Golenser

Research output: Contribution to journalArticlepeer-review

109 Scopus citations

Abstract

Some structural properties of the DNA of Plasmodium falciparum were studied thoroughly using several techniques. Its G+C content was found to be extremely low (17-19%), the lowest reported for a living organism. The DNA seems to be composed only of the four major bases as no methylated bases were detected. This DNA had a Tm value of 62.5°C and its denaturation profile showed no marked intramolecular heterogeneity.

Original languageEnglish
Pages (from-to)539-546
Number of pages8
JournalNucleic Acids Research
Volume10
Issue number2
DOIs
StatePublished - 22 Jan 1982
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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