The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

Laura Governini, Raoul Orvieto, Cristiana Guerranti, Laura Gambera, Vincenzo De Leo, Paola Piomboni

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R∈=∈0.75; P∈<∈0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p∈<∈0.02) and number of embryos transferred (p∈<∈0.02), compared to the PFC negative group.

Original languageEnglish
Pages (from-to)415-418
Number of pages4
JournalJournal of Assisted Reproduction and Genetics
Volume28
Issue number5
DOIs
StatePublished - 1 May 2011

Keywords

  • Follicular fluid
  • IVF
  • Infertility
  • PFC contamination

ASJC Scopus subject areas

  • Reproductive Medicine
  • Genetics
  • Obstetrics and Gynecology
  • Developmental Biology
  • Genetics(clinical)

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