The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

Laura Governini; Raoul Orvieto; Cristiana Guerranti; Laura Gambera; Vincenzo De Leo; Paola Piomboni

doi:10.1007/s10815-011-9548-2

The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

Laura Governini
, Raoul Orvieto
, Cristiana Guerranti
, Laura Gambera
, Vincenzo De Leo
, Paola Piomboni

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R∈=∈0.75; P∈<∈0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p∈<∈0.02) and number of embryos transferred (p∈<∈0.02), compared to the PFC negative group.

Original language	English
Pages (from-to)	415-418
Number of pages	4
Journal	Journal of Assisted Reproduction and Genetics
Volume	28
Issue number	5
DOIs	https://doi.org/10.1007/s10815-011-9548-2
State	Published - 1 May 2011

Keywords

Follicular fluid
IVF
Infertility
PFC contamination

ASJC Scopus subject areas

Reproductive Medicine
Genetics
Obstetrics and Gynecology
Developmental Biology
Genetics(clinical)

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10.1007/s10815-011-9548-2

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title = "The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity",

abstract = "In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R∈=∈0.75; P∈<∈0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p∈<∈0.02) and number of embryos transferred (p∈<∈0.02), compared to the PFC negative group.",

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AU - Governini, Laura

AU - Orvieto, Raoul

AU - Guerranti, Cristiana

AU - Gambera, Laura

AU - De Leo, Vincenzo

AU - Piomboni, Paola

PY - 2011/5/1

Y1 - 2011/5/1

N2 - In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R∈=∈0.75; P∈<∈0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p∈<∈0.02) and number of embryos transferred (p∈<∈0.02), compared to the PFC negative group.

AB - In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R∈=∈0.75; P∈<∈0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p∈<∈0.02) and number of embryos transferred (p∈<∈0.02), compared to the PFC negative group.

KW - Follicular fluid

KW - IVF

KW - Infertility

KW - PFC contamination

UR - https://www.scopus.com/pages/publications/80051552331

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SP - 415

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JO - Journal of Assisted Reproduction and Genetics

JF - Journal of Assisted Reproduction and Genetics

IS - 5

ER -

The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

Abstract

Keywords

ASJC Scopus subject areas

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