The impact of intracoronary thrombus aspiration on STEMI outcomes

Sa'ar Minha, Ran Kornowski, Hana Vaknin-Assa, Danny Dvir, Eldad Rechavia, Igal Teplitsky, David Brosh, Tamir Bental, Nurit Shor, Alexander Battler, Eli Lev, Abid Assali

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background: Manual coronary thrombus aspiration was associated with improved outcomes of ST-elevation myocardial infarction (STEMI) patients. We aimed to evaluate the outcome of aspiration in a "real-world" setting of primary percutaneous coronary intervention (PPCI). Methods and materials: We analyzed the outcome of STEMI patients who underwent PPCI (initial Thrombolysis in Myocardial Infarction flow grade 0/1), comparing patients who underwent aspiration (ASP) to those who had standard (STD) therapy. Various subgroups outcomes were further analyzed. Clinical end points included mortality and major adverse cardiovascular events (MACE) at 30 days and at 1 year. Results: One thousand thirty-five consecutive patients were included: 189 (18.26%) with ASP and 846 (81.74%) with STD. ASP patients were younger (58±12 vs. 61±13, P<.05) and had higher incidence of direct stenting compared to STD patients (34% vs. 16.7%, P<.05). No significant differences were noted in the outcome of ASP vs. STD at 30 days (mortality rate 4.2% vs. 4.5%, P=9; MACE 6.9% vs. 9.8%, P=2) and at 1 year (mortality rate 8.0% vs. 8.3%, P=9; MACE 20.0% vs. 22.3%, P=5). A significant advantage in favor of ASP was evident in patients with proximal culprit lesions, anterior infarcts, and right ventricular involvement. Conclusions: Although this was largely a negative study, when STEMI involved a large jeopardized myocardium, aspiration was associated with sustained improved clinical outcomes.

Original languageEnglish
Pages (from-to)167-171
Number of pages5
JournalCardiovascular Revascularization Medicine
Issue number3
StatePublished - 1 May 2012
Externally publishedYes


  • Aspiration
  • PCI, percutaneous coronary intervention
  • ST-elevation myocardial infarction
  • Thrombectomy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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