The incidence and prognosis of renal dysfunction following cardioversion of atrial fibrillation

Yaron Hellman, Matan J. Cohen, David Leibowitz, Sasa Loncar, David Gozal, Yosef S. Haviv, Guy Haber, Mohamad Afifi, Shimon Rosenheck, Chaim Lotan, Arthur Pollak, Dan Gilon

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: Limited data are available regarding the incidence and clinical impact of renal dysfunction following cardioversion of atrial fibrillation. The objective of this study was to assess the incidence and implications of renal dysfunction following cardioversion of atrial fibrillation. Methods: We conducted a nested case-control study to determine the incidence, timing, risk factors and outcome of atrial fibrillation cardioversion associated with renal dysfunction (AFCARD) in a tertiary medical center. Consecutive patients undergoing direct current cardioversion (DCCV) for atrial fibrillation in our institution during 2008-2009 with measurements of creatinine before and following cardioversion were included. AFCARD was defined as a rise in serum creatinine greater than 25% from baseline within a week following DCCV. Results: One hundred and twelve patients were included in the study, of whom 19 (17%) developed AFCARD. One patient required hemodialysis. Patients with AFCARD had a higher incidence of advanced heart failure, diabetes mellitus and were more frequently treated with digoxin and enoxaparin. Patients with AFCARD had a significantly decreased survival rate at 1 year (63 vs. 92%; p < 0.001). Conclusions: AFCARD is relatively common and is associated with increased mortality. These findings suggest a role for close surveillance of renal function following DCCV.

Original languageEnglish
Pages (from-to)184-189
Number of pages6
JournalCardiology
Volume124
Issue number3
DOIs
StatePublished - 1 Jan 2013
Externally publishedYes

Keywords

  • Acute renal failure
  • Atrial fibrillation
  • Cardioversion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

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