The Influence of Leukocytes on the Activity of Cardiovascular System in Women with High Blood Pressure

B. I. Kuznik, S. O. Davydov, E. S. Guseva, A. V. Stepanov, Y. N. Smolyakov, I. V. Fine, E. Magen

Research output: Contribution to journalArticlepeer-review


Abstract: Thirty apparently healthy elderly women and 72 women diagnosed with Hypertensive Heart Disease (HHD) participated in the study. The subjects with hypertension were divided into two groups: the first group (HHD-1) included women receiving medication; the second group (HHD-2) included women receiving medication and kinesiotherapy (three or four courses regularly during the past two to three years). In elderly women with a high blood pressure, the total number of lymphocytes and eosinophils was higher than in healthy women. The women with hypertension also had higher values of stroke volume (SV), left ventricular end diastolic volume (LVEDV), cardiac output (CO), left ventricular mass (LVDM), and left ventricular mass index (LVMI). In women with hypertension, the balance of velocity distribution in the arteries and microvasculature was shifted toward the fast interlayer processes. In women who exercised regularly, these changes were much smaller. In both healthy women and women with hypertension, there was an association between the total leukocyte count, individual types of leukocytes, the level of blood pressure, and hemodynamic parameters. The strongest relationships were observed between the number of eosinophils and the blood pressure.

Original languageEnglish
Pages (from-to)649-657
Number of pages9
JournalHuman Physiology
Issue number6
StatePublished - 1 Nov 2019


  • cardiodynamics
  • eosinophils
  • hemodynamics
  • hypertension
  • leukocytes
  • lymphocytes
  • moderate exercise
  • monocytes
  • neutrophils

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)


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