The leukocyte adherence inhibition test (lai) in preoperative diagnosis of epithelial ovarian cancer

R. Dgani; A. Shani; U. Elchalal; N. Harpaz; Z. Bentwich; A. Fink

doi:10.1006/gyno.1993.1138

The leukocyte adherence inhibition test (lai) in preoperative diagnosis of epithelial ovarian cancer

R. Dgani, A. Shani, U. Elchalal, N. Harpaz, Z. Bentwich, A. Fink

Research output: Contribution to journal › Article › peer-review

Abstract

One hundred two women admitted for evaluation of an adenexal mass were tested prior to surgery by the computerized tube leukocyte adherence inhibition (LAI) assay. The test was positive in 24/35 (69%) patients, diagnosed after surgery as epithelial ovarian cancer while 50/67 (75%) of those diagnosed as benign masses were negative. Only 2/38 (5%) of normal control subjects showed a false-positive result. The LAI test described in this report showed a sensitivity of 88% and a specificity of 75% in stage I ovarian cancer; thus it may be useful for early diagnosis of ovarian malignancy.

Original language	English
Pages (from-to)	349-353
Number of pages	5
Journal	Gynecologic Oncology
Volume	49
Issue number	3
DOIs	https://doi.org/10.1006/gyno.1993.1138
State	Published - 1 Jan 1993
Externally published	Yes

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1006/gyno.1993.1138

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title = "The leukocyte adherence inhibition test (lai) in preoperative diagnosis of epithelial ovarian cancer",

abstract = "One hundred two women admitted for evaluation of an adenexal mass were tested prior to surgery by the computerized tube leukocyte adherence inhibition (LAI) assay. The test was positive in 24/35 (69%) patients, diagnosed after surgery as epithelial ovarian cancer while 50/67 (75%) of those diagnosed as benign masses were negative. Only 2/38 (5%) of normal control subjects showed a false-positive result. The LAI test described in this report showed a sensitivity of 88% and a specificity of 75% in stage I ovarian cancer; thus it may be useful for early diagnosis of ovarian malignancy.",

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AU - Shani, A.

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AU - Harpaz, N.

AU - Bentwich, Z.

AU - Fink, A.

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AB - One hundred two women admitted for evaluation of an adenexal mass were tested prior to surgery by the computerized tube leukocyte adherence inhibition (LAI) assay. The test was positive in 24/35 (69%) patients, diagnosed after surgery as epithelial ovarian cancer while 50/67 (75%) of those diagnosed as benign masses were negative. Only 2/38 (5%) of normal control subjects showed a false-positive result. The LAI test described in this report showed a sensitivity of 88% and a specificity of 75% in stage I ovarian cancer; thus it may be useful for early diagnosis of ovarian malignancy.

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ER -

The leukocyte adherence inhibition test (lai) in preoperative diagnosis of epithelial ovarian cancer

Abstract

ASJC Scopus subject areas

UN SDGs

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