The locust foraging gene

C. Lucas, R. Kornfein, M. Chakaborty-Chatterjee, J. Schonfeld, N. Geva, M. B. Sokolowski, A. Ayali

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Our knowledge of how genes act on the nervous system in response to the environment to generate behavioral plasticity is limited. A number of recent advancements in this area concern food-related behaviors and a specific gene family called foraging (for), which encodes a cGMPdependent protein kinase (PKG). The desert locust (Schistocerca gregaria) is notorious for its destructive feeding and long-term migratory behavior. Locust phase polyphenism is an extreme example of environmentally induced behavioral plasticity. In response to changes in population density, locusts dramatically alter their behavior, from solitary and relatively sedentary behavior to active aggregation and swarming. Very little is known about the molecular and genetic basis of this striking behavioral phenomenon. Here we initiated studies into the locust for gene by identifying, cloning, and studying expression of the gene in the locust brain. We determined the phylogenetic relationships between the locust PKG and other known PKG proteins in insects. FOR expression was found to be confined to neurons of the anterior midline of the brain, the pars intercerebralis. Our results suggest that differences in PKG enzyme activity are correlated to well-established phase-related behavioral differences. These results lay the groundwork for functional studies of the locust for gene and its possible relations to locust phase polyphenism.

Original languageEnglish
Pages (from-to)52-66
Number of pages15
JournalArchives of Insect Biochemistry and Physiology
Volume74
Issue number1
DOIs
StatePublished - 1 May 2010
Externally publishedYes

Keywords

  • Density-dependent phase polyphenism
  • Foraging gene
  • Kinase
  • Locust
  • Swarming behavior

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Insect Science

Fingerprint

Dive into the research topics of 'The locust foraging gene'. Together they form a unique fingerprint.

Cite this