The mood response and plasma cyclic-AMP response to intravenous methylphenidate

R. Kadouch, R. H. Belmaker, R. P. Ebstein, L. Peres

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Plasma cyclic-AMP responses to adrenergic agonists are due to stimulation of the peripheral β-adrenergic receptor. Mood responses to stimulants are thought to be due to actions leading to stimulation of central catecholamine receptors. To determine if a peripheral measure of receptor sensitivity could predict central mood effects of stimulants, the plasma cyclic-AMP response and the mood response to intravenous methylphenidate were determined simultaneously in 13 subjects. No correlation between the two responses was found.

Original languageEnglish
Pages (from-to)250-255
Number of pages6
Issue number4
StatePublished - 1 Jan 1977
Externally publishedYes

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Psychiatry and Mental health
  • Biological Psychiatry


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