The mood response and plasma cyclic-AMP response to intravenous methylphenidate

R. Kadouch; R. H. Belmaker; R. P. Ebstein; L. Peres

doi:10.1159/000117610

The mood response and plasma cyclic-AMP response to intravenous methylphenidate

R. Kadouch, R. H. Belmaker, R. P. Ebstein, L. Peres

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Plasma cyclic-AMP responses to adrenergic agonists are due to stimulation of the peripheral β-adrenergic receptor. Mood responses to stimulants are thought to be due to actions leading to stimulation of central catecholamine receptors. To determine if a peripheral measure of receptor sensitivity could predict central mood effects of stimulants, the plasma cyclic-AMP response and the mood response to intravenous methylphenidate were determined simultaneously in 13 subjects. No correlation between the two responses was found.

Original language	English
Pages (from-to)	250-255
Number of pages	6
Journal	Neuropsychobiology
Volume	3
Issue number	4
DOIs	https://doi.org/10.1159/000117610
State	Published - 1 Jan 1977
Externally published	Yes

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000117610

Cite this

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The mood response and plasma cyclic-AMP response to intravenous methylphenidate

Abstract

ASJC Scopus subject areas

UN SDGs

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