The potential longevity-promoting hypoxic-hypercapnic environment as a measure for radioprotection

Elroei David, Marina Wolfson, Khachik K. Muradian, Vadim E. Fraifeld

Research output: Contribution to journalArticlepeer-review

Abstract

Many biological mechanisms of aging well converge with radiation’s biological effects. We used scientific insights from the field of aging to establish a novel hypoxic-hypercapnic environment (HHE) concept for radioprotection. According to this concept, HHE which possesses an anti-aging and longevity-promoting potential, should also act as a radiomitigator and radioprotector. As such, it might contribute greatly to the safety and wellbeing of individuals exposed to high levels of radiation, whether in planned events (e.g. astronauts) or in unplanned events (e.g. first responders in nuclear accidents).

Original languageEnglish
Pages (from-to)891-898
Number of pages8
JournalBiogerontology
Volume25
Issue number5
DOIs
StatePublished - 1 Oct 2024

Keywords

  • Aging
  • Hormesis
  • Hypercapnia
  • Hypoxia
  • Ionizing radiation
  • Radioprotection

ASJC Scopus subject areas

  • Aging
  • Gerontology
  • Geriatrics and Gerontology

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