The role of intravenous albumin in the prevention of severe ovarian hyperstimulation syndrome: A pilot experimental study

  • R. Orvieto
  • , R. Abir
  • , B. Kaplan
  • , I. Bar-Hava
  • , Z. Ben-Rafael

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Objective: To evaluate the role of intravenous albumin in the prevention of severe ovarian hyperstimulation syndrome (OHSS). Design: A pilot experimental study. Material and Methods: Ovarian hyperstimulation was induced in 5 rabbits using human menopausal gonadotropin/human chorionic gonadotropin, after pretreatment without (control group) or with bovine serum albumin (BSA group). Results: Despite an increase in serum protein levels, the BSA group showed comparable Δ increase in body weight and degree of ascites formation. Conclusions: Intravenous albumin did not prevent severe OHSS in a rabbit model despite the observed increase in serum oncotic pressure.

Original languageEnglish
Pages (from-to)98-99
Number of pages2
JournalClinical and Experimental Obstetrics and Gynecology
Volume26
Issue number2
StatePublished - 21 Jul 1999
Externally publishedYes

Keywords

  • Albumin
  • OHSS
  • Prevention

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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