The role of L1 in the progression of ovarian carcinomas

Peter Altevogt; M. Fogel

doi:10.1055/s-2004-832304

The role of L1 in the progression of ovarian carcinomas

Peter Altevogt, M. Fogel

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The L1 molecule has recently emerged as a promising new biomarker for the prognosis of human ovarian and endometrial tumors. It was initially described as an adhesion molecule for the development of the nervous system but its function in tumor cells is not well known. In this article we summerize recent data on the role of L1 in promoting tumor cell adhesion and migration and in gene regulation. We address the question how L1 determination in tumor tissue samples and in serum and ascites could potentially improve the disease management.

Original language	English
Pages (from-to)	323-325
Number of pages	3
Journal	Zentralblatt fur Gynakologie
Volume	126
Issue number	5
DOIs	https://doi.org/10.1055/s-2004-832304
State	Published - 1 Oct 2004
Externally published	Yes

Keywords

ADAM10
Cell migration
L1
Ovarian and endometrial carcinoma
Shedding

ASJC Scopus subject areas

Obstetrics and Gynecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/s-2004-832304

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abstract = "The L1 molecule has recently emerged as a promising new biomarker for the prognosis of human ovarian and endometrial tumors. It was initially described as an adhesion molecule for the development of the nervous system but its function in tumor cells is not well known. In this article we summerize recent data on the role of L1 in promoting tumor cell adhesion and migration and in gene regulation. We address the question how L1 determination in tumor tissue samples and in serum and ascites could potentially improve the disease management.",

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AU - Fogel, M.

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AB - The L1 molecule has recently emerged as a promising new biomarker for the prognosis of human ovarian and endometrial tumors. It was initially described as an adhesion molecule for the development of the nervous system but its function in tumor cells is not well known. In this article we summerize recent data on the role of L1 in promoting tumor cell adhesion and migration and in gene regulation. We address the question how L1 determination in tumor tissue samples and in serum and ascites could potentially improve the disease management.

KW - ADAM10

KW - Cell migration

KW - L1

KW - Ovarian and endometrial carcinoma

KW - Shedding

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JF - Zentralblatt fur Gynakologie

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ER -

The role of L1 in the progression of ovarian carcinomas

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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