The role of tissue plasminogen activator in the successful treatment of infected cardiac thrombus in children

Eli Zalzstein, Nili Zucker, Aviva Levitas

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Infected cardiac thrombus is rare in children, with antibiotic or antifungal agents used as the first line of treatment. Persistence is an indication for surgical intervention. We describe two children who were treated successfully with a combination of antibiotic and antithrombotic agents. Use of antithrombotic agents promotes degeneration of fibrin, thus reducing the mass and facilitating the diffusion of the antibiotic and/or antifungal agents.

Original languageEnglish
Pages (from-to)355-356
Number of pages2
JournalCardiology in the Young
Volume11
Issue number3
DOIs
StatePublished - 1 Jan 2001
Externally publishedYes

Keywords

  • Infected cardiac thrombus
  • Plasminogen

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

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