The role of trace elements in psoriatic patients undergoing balneotherapy with Dead Sea bath salt

Sima Halevy, Hani Giryes, Michael Friger, Nili Grossman, Zeev Karpas, Batia Sarov, Shaul Sukenik

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Background: A beneficial effect was observed in patients with psoriasis vulgaris following balneotherapy with Dead Sea bath salt. Objectives: To evaluate the possible role of trace elements in the effectiveness of balneotherapy. Methods: Serum levels of 11 trace elements were analyzed in 23 patients with psoriasis vulgaris who participated in a double-blind controlled study of balneotherapy with either Dead Sea bath salt (12 patients) or common salt (11 patients). Thirteen healthy volunteers served as controls. Results: The mean pre-treatment serum levels of boron, cadmium, lithium and rubidium were significantly lower in patients compared to controls, whereas the mean pre-treatment serum level of manganese was significantly higher in patients compared to controls. Balneotherapy with Dead Sea bath salt resulted in a significant decrease (P = 0.0051) in the mean serum level of manganese from 0.10 ± 0.05 mol/L to 0.05 ± 0.02 μmol/L. The mean reduction in the serum level of manganese differed significantly (P = 0.002) between responders (% Psoriasis Area and Severity Index score reduction ≥ 25) and non-responders (% PASI score reduction < 25). Following balneotherapy with Dead Sea bath salt the mean serum level of lithium decreased in responders by 0.01 ± 0.02 μmol/L, whereas its level in non-responders increased by 0.03 ± 0.03 μmol/L. (P = 0.015). Conclusions: Manganese and lithium may play a role in the effectiveness of balneotherapy with Dead Sea bath salt for psoriasis.

Original languageEnglish
Pages (from-to)828-832
Number of pages5
JournalIsrael Medical Association Journal
Volume3
Issue number11
StatePublished - 1 Dec 2001
Externally publishedYes

Keywords

  • Balneotherapy
  • Bath
  • Dead Sea
  • Lithium
  • Manganese
  • Psoriasis
  • Salt
  • Spa
  • Trace elements

ASJC Scopus subject areas

  • General Medicine

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