The stereochemistry of a nine-membered ring analogue of nefopam, a nonnarcotic analgesic drug

Keyphrases

• Proton 100%
• Opioid Analgesics 100%
• C(V) 100%
• Major Species 100%
• Analgesic Drugs 100%
• Stereochemistry 100%
• Solution State 100%
• Nine-membered Ring 100%
• Nefopam 100%
• Minor Species 100%
• N-methylation 50%
• Ambient Temperature 50%
• Two-species 50%
• Hydrochloride 50%
• X-ray Diffraction (XRD) Analysis 50%
• Coupling Constant 50%
• Monoclinic 50%
• Configuration Space 50%
• Ratio Method 50%
• NMR Spectra 50%
• Phenyl 50%
• Solid-state Structures 50%
• Slow Exchange 50%
• Dihedral Angle 50%
• Conformational Heterogeneity 50%
• Nitrogen Inversion 50%
• Antiperiplanar 50%
• Fragment Coupling 50%
• Vicinal Coupling Constants 50%
• Prototropic Shift 50%
• R-ratio 50%

Chemistry

• Stereochemistry 100%
• Nefopam 100%
• Antalgic Agent 100%
• X-Ray Diffraction 50%
• Space Group 50%
• Single Crystal X-Ray Diffraction 50%
• P21 50%
• Dihedral Angle 50%
• NMR Spectrum 50%
• Nitrogen Inversion 50%