The subcranial approach for anterior skull base tumors

Dan M. Fliss, Gideon Zucker, Aharon Amir, Albert Gatot, Jacob T. Cohen, Sergei Spektor

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


The purpose of this study is to present the technique of the extended subcranial approach to the anterior skull base, and to review the results of 48 patients who underwent the procedure. A retrospective review was conducted on the records of 48 patients who underwent this procedure for the treatment of various neoplasms originating in the nasal cavity, nasopharynx, paranasal sinuses, orbit, or meninges, in an academic tertiary referral medical center. Preoperative patient evaluation, surgical technique, and complications are also reviewed.Sixteen patients had malignant tumors and 32 patients had benign tumors. There was one perioperative death (fulminant meningitis on postoperative day 28). Significant complications consisted of meningitis occurring in 2 patients and 5 cases of osteoradionecrosis with bone cutaneous fistula. The most common late complication was anosmia (in 27 patients).Based on this review, we feel that the extended subcranial approach to the anterior skull base is a safe, versatile, and effective procedure for the surgical treatment of tumors that involve the anterior skull base.

Original languageEnglish
Pages (from-to)238-253
Number of pages16
JournalOperative Techniques in Otolaryngology - Head and Neck Surgery
Issue number4
StatePublished - 1 Dec 2000
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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