The use of commercial saponin from Quillaja saponaria bark as a natural larvicidal agent against Aedes aegypti and Culex pipiens

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    69 Scopus citations

    Abstract

    The larvicidal activity of commercial bark saponin extract (Sigma) from Quillaja saponaria was studied on 3rd-4th instar larvae of Aedes aegypti and Culex pipiens (vectors for dengue fever and Western Nile virus, respectively). The larvae were exposed to serial concentrations (1000, 800, 500, 300, 100, 10, 1, 0.1 and 0.01 mg/l) of the extract for 1, 3, 5, 7 and 11 days. The results indicate that commercial bark saponin is toxic, causing 100% larval mortality in A. aegypti and C. pipiens after 1 and 5 days at a dosage of 800 and 1000 mg/l, respectively. Interestingly, while bark saponins had a toxic effect on larvae there was no effect on egg hatchability in either species. The results obtained suggest that, in addition to their known activities, saponins can also serve as natural larvicidal compounds.

    Original languageEnglish
    Pages (from-to)407-409
    Number of pages3
    JournalJournal of Ethnopharmacology
    Volume81
    Issue number3
    DOIs
    StatePublished - 30 Jul 2002

    Keywords

    • Aedes aegypti
    • Culex pipiens
    • Larvicidal activity
    • Quillaja saponaria
    • Saponins

    ASJC Scopus subject areas

    • Pharmacology
    • Drug Discovery

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