The Value of Neurological Assessment for Prediction of Subtle Cerebral Infarction

Anat Horev, Yonatan Serlin, Ron Eshel, Ronen Leker, Michael Star, Asaf Honig, Gal Ifergane

Research output: Contribution to journalArticlepeer-review


We examined to what extent clinical assessment alone can predict subtle acute cerebral infarction on magnetic resonance imaging (MRI). Of the 72 patients presented to the emergency department (ED) with transient neurological deficits, 26 (36.1%) were predicted to be positive and 46 (63.9%) negative for transient ischemic attack/minor stroke by two independent neurologists. Twenty patients (27.8%) had acute restricted diffusion on MRI. Clinical assessment showed substantial agreement with MRI findings (Kappa = 0.75), sensitivity (95.0%), specificity (86.5%), positive-likelihood ratio 7.06, and negative-likelihood ratio 0.06. Neurological assessment has an excellent predicting value for MRI-confirmed acute cerebral infarction and a key role in the facilitation of effective patient care in the ED.

Original languageEnglish
Pages (from-to)275-277
Number of pages3
JournalCanadian Journal of Neurological Sciences
Issue number2
StatePublished - 1 Mar 2021
Externally publishedYes


  • Diffusion-weighted imaging
  • Stroke
  • Transient ischemic attack

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


Dive into the research topics of 'The Value of Neurological Assessment for Prediction of Subtle Cerebral Infarction'. Together they form a unique fingerprint.

Cite this