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The worst case complexity of maximum parsimony

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    1 Scopus citations

    Abstract

    One of the core classical problems in computational biology is that of constructing the most parsimonious phylogenetic tree interpreting an input set of sequences from the genomes of evolutionarily related organisms. We re-examine the classical Maximum Parsimony (MP) optimization problem for the general (asymmetric) scoring matrix case, where rooted phylogenies are implied, and analyze theworst case bounds of three approaches to MP: The approach of Cavalli-Sforza and Edwards [5], the approach of Hendy and Penny [12], and a new agglomerative, "bottomup" approach we present in this paper. We show that the second and third approaches are faster than the first by a factor of and Θ(n), respectively.

    Original languageEnglish
    Title of host publicationCombinatorial Pattern Matching - 25th Annual Symposium, CPM 2014, Proceedings
    PublisherSpringer Verlag
    Pages79-88
    Number of pages10
    ISBN (Print)9783319075655
    DOIs
    StatePublished - 1 Jan 2014
    Event25th Annual Symposium on Combinatorial Pattern Matching, CPM 2014 - Moscow, Russian Federation
    Duration: 16 Jun 201418 Jun 2014

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Volume8486 LNCS
    ISSN (Print)0302-9743
    ISSN (Electronic)1611-3349

    Conference

    Conference25th Annual Symposium on Combinatorial Pattern Matching, CPM 2014
    Country/TerritoryRussian Federation
    CityMoscow
    Period16/06/1418/06/14

    ASJC Scopus subject areas

    • Theoretical Computer Science
    • General Computer Science

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