Thou shalt not cleave DNA—only repress transcription: A compact Cas protein representing a new CRISPR-Cas subtype

Tridib Mahata; Udi Qimron

doi:10.1016/j.molcel.2022.10.021

Thou shalt not cleave DNA—only repress transcription: A compact Cas protein representing a new CRISPR-Cas subtype

Tridib Mahata
, Udi Qimron

Research output: Contribution to journal › Comment/debate

Abstract

Wu et al.¹ characterize Cas12m, a compact Cas protein that silences transcription without cleaving DNA and is a prototype protein of the novel CRISPR-Cas subtype V-M.

Original language	English
Pages (from-to)	4403-4404
Number of pages	2
Journal	Molecular Cell
Volume	82
Issue number	23
DOIs	https://doi.org/10.1016/j.molcel.2022.10.021
State	Published - 1 Dec 2022
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2022.10.021

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title = "Thou shalt not cleave DNA—only repress transcription: A compact Cas protein representing a new CRISPR-Cas subtype",

abstract = "Wu et al.1 characterize Cas12m, a compact Cas protein that silences transcription without cleaving DNA and is a prototype protein of the novel CRISPR-Cas subtype V-M.",

author = "Tridib Mahata and Udi Qimron",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = dec,

day = "1",

doi = "10.1016/j.molcel.2022.10.021",

language = "English",

volume = "82",

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journal = "Molecular Cell",

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T1 - Thou shalt not cleave DNA—only repress transcription

T2 - A compact Cas protein representing a new CRISPR-Cas subtype

AU - Mahata, Tridib

AU - Qimron, Udi

PY - 2022/12/1

Y1 - 2022/12/1

N2 - Wu et al.1 characterize Cas12m, a compact Cas protein that silences transcription without cleaving DNA and is a prototype protein of the novel CRISPR-Cas subtype V-M.

AB - Wu et al.1 characterize Cas12m, a compact Cas protein that silences transcription without cleaving DNA and is a prototype protein of the novel CRISPR-Cas subtype V-M.

UR - https://www.scopus.com/pages/publications/85142425760

U2 - 10.1016/j.molcel.2022.10.021

DO - 10.1016/j.molcel.2022.10.021

M3 - Comment/debate

C2 - 36459982

AN - SCOPUS:85142425760

SN - 1097-2765

VL - 82

SP - 4403

EP - 4404

JO - Molecular Cell

JF - Molecular Cell

IS - 23

ER -

Thou shalt not cleave DNA—only repress transcription: A compact Cas protein representing a new CRISPR-Cas subtype

Abstract

ASJC Scopus subject areas

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