Three-dimensional nano-localization of single fluorescent emitters

Iwan Märki, Noelia L. Bocchio, Stefan Geissbuehler, François Aguet, Alberto Bilenca, Theo Lasser

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We present a combination of self-interference microscopy with lateral super-resolution microscopy and introduce a novel approach for localizing a single nano-emitter to within a few nanometers in all three dimensions over a large axial range. We demonstrate nanometer displacements of quantum dots placed on top of polymer bilayers that undergo swelling when changing from an air to a water environment, achieving standard deviations below 10 nm for axial and lateral localization.

Original languageEnglish
Pages (from-to)20263-20272
Number of pages10
JournalOptics Express
Issue number19
StatePublished - 13 Sep 2010
Externally publishedYes


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