Thrombotic thrombocytopenic purpura due to alcohol binge drinking

Doron Zamir, Ilia Polychuck, Ilan Leibovitz, Tatiana Reitblat, Arnaldo Ducach, Gilles Lugassy

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Binge alcohol drinking is a pattern of alcohol abuse that is common among young males worldwide. It has been found to be associated with an increased likelihood of injury as a cause of death. Chronic alcohol abuse is known to cause some common hematological manifestations such as macrocytosis, thrombocytopenia, sideroblastic anemia, global marrow suppression, and folic acid deficiency anemia. We present a rare case involving an unusual and severe hematological manifestation of binge alcohol drinking: thrombotic thrombocytopenic purpura (TTP). The patient we present had severe and prolonged TTP necessitating prolonged treatment with plasmapheresis and plasma exchange. We discuss the relevant medical literature and the possible physiopathology of this complication.

Original languageEnglish
Pages (from-to)262-263
Number of pages2
JournalEuropean Journal of Internal Medicine
Issue number4
StatePublished - 1 Jul 2004


  • Alcohol
  • Binge drinking
  • Thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Internal Medicine


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