Thymus-derived lymphocytes: Humoral and cellular reactions distinguished by hydrocortisone

Shraga Segal, Irun R. Cohen, Michael Feldman

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Lymphocytes derived from the thymus (T cells) take part in the induction of humoral antibody and also effect cell-mediated graft-versus-host reactions. Preliminary treatment of mice with hydrocortisone caused an inhibition of T-cell function in humoral immunity, while enhancing the graft-versus-host reactivity of the same population of spleen cells. This suggests that different types of T cells participate in cellular and humoral immune reactions.

Original languageEnglish
Pages (from-to)1126-1128
Number of pages3
Issue number4026
StatePublished - 1 Jan 1972
Externally publishedYes

ASJC Scopus subject areas

  • General


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