Thyroid hormones in chronic heat exposed men

A. Gertner, R. Israeli, A. Lev, Y. Cassuto

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations


    Previous reports have indicated that thyroid gland activity, is depressed in the heat. Total thyroxine (T4) and triiodothyronine (T3) serum levels in 17 workers of the metal work shop at a plant near the Dead Sea and 8 workers in Beer Sheva, Israel were examined. The metal workshop of the plant near the Dead Sea is part of a large chemical plant. The one in Beer Sheva is part of a large construction company. Maintenance work, as well as metal work projects are performed in both workshops. During the work shifts, the workers of the Dead Sea plant were exposed to temperatures ranging from 30-36°C (May-Oct.) and 14-21°C (Dec.-Feb). In Beer Sheva the range was 25-32°C (June-Sept.) and 10- 17°C (Dec.-Feb.). Total T4 was measured by competitive protein binding and total T3 by radioimmunoassay in blood drawn before work (0700) in July and January. In summer. T4 was higher and T3 was lower for both groups than in winter. The observed summer T3 decrease may result from depressed extrathyroidal conversion of T4 to T3. We conclude that the regulation of energy metabolism in hot climates may be related to extrathyroidal conversion of T4 to T3.

    Original languageEnglish
    Pages (from-to)75-82
    Number of pages8
    JournalInternational Journal of Biometeorology
    Issue number1
    StatePublished - 1 Mar 1983

    ASJC Scopus subject areas

    • Ecology
    • Atmospheric Science
    • Health, Toxicology and Mutagenesis


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