TY - JOUR
T1 - Timing of bimanual movements in human and non-human primates in relation to neuronal activity in primary motor cortex and supplementary motor area
AU - Gribova, A.
AU - Donchin, O.
AU - Bergman, H.
AU - Vaadia, E.
AU - Cardoso De Oliveira, S.
N1 - Funding Information:
The research was supported in part by the Israel Science Foundation, the Israel Academy of Sciences and Humanities, the United States-Israel Binational Science Foundation, the German-Israeli Foundation for Scientific Research and Development (GIF), the Volkswagen Foundation and the DFG (CA 245/1-1). We thank the MINERVA Foundation, which supported S.C.d.O. as a postdoctoral fellow, the Mifal Hapise Foundation for a fellowship to A.G. and the Clore Foundation for a fellowship to O.D.
PY - 2002/1/1
Y1 - 2002/1/1
N2 - This study investigates the timing of bimanual movements in a combined behavioral and physiological approach. Human subjects and rhesus monkeys performed the same bimanual task. In monkeys, we simultaneously recorded neuronal activity in the two hemispheres of primary motor cortex (MI) or supplementary motor area (SMA), and related it to bimanual coordination in the temporal domain. Both for monkeys and humans, the reaction times of bimanual movements never significantly exceeded the reaction times of the slower arm in unimanual movements. Consistent with this, the longest delay between neural activity onset in SMA and MI and movement initiation was observed in unimanual movements of the slower arm and not in bimanual movements. Both results suggest that the programming of bimanual movements does not require more processing time than unimanual movements. They are also consistent with the view that bimanual movements are programmed in a single process, rather than by combining two separate unimanual movement plans. In both humans and monkeys, movement initiation was highly correlated between the arms. However, once movements began, the temporal correlation between the arms progressively declined. Movement decorrelation was accompanied by a net decorrelation of neuronal population activity in MI and SMA, suggesting a functional connection between neuronal interactions and the level of bimanual coupling and decoupling. The similarity of neuronal activities in MI and SMA in relationship to behavioral timing lends support to the idea that both areas are involved in the temporal coordination of the arms.
AB - This study investigates the timing of bimanual movements in a combined behavioral and physiological approach. Human subjects and rhesus monkeys performed the same bimanual task. In monkeys, we simultaneously recorded neuronal activity in the two hemispheres of primary motor cortex (MI) or supplementary motor area (SMA), and related it to bimanual coordination in the temporal domain. Both for monkeys and humans, the reaction times of bimanual movements never significantly exceeded the reaction times of the slower arm in unimanual movements. Consistent with this, the longest delay between neural activity onset in SMA and MI and movement initiation was observed in unimanual movements of the slower arm and not in bimanual movements. Both results suggest that the programming of bimanual movements does not require more processing time than unimanual movements. They are also consistent with the view that bimanual movements are programmed in a single process, rather than by combining two separate unimanual movement plans. In both humans and monkeys, movement initiation was highly correlated between the arms. However, once movements began, the temporal correlation between the arms progressively declined. Movement decorrelation was accompanied by a net decorrelation of neuronal population activity in MI and SMA, suggesting a functional connection between neuronal interactions and the level of bimanual coupling and decoupling. The similarity of neuronal activities in MI and SMA in relationship to behavioral timing lends support to the idea that both areas are involved in the temporal coordination of the arms.
KW - Bimanual coordination
KW - MI
KW - Motor psychophysics
KW - SMA
KW - Temporal coordination
UR - http://www.scopus.com/inward/record.url?scp=0036381975&partnerID=8YFLogxK
U2 - 10.1007/s00221-002-1174-x
DO - 10.1007/s00221-002-1174-x
M3 - Article
C2 - 12232689
AN - SCOPUS:0036381975
SN - 0014-4819
VL - 146
SP - 322
EP - 335
JO - Experimental Brain Research
JF - Experimental Brain Research
IS - 3
ER -