Tissue engineering on the nanoscale: Lessons from the heart

Sharon Fleischer; Tal Dvir

doi:10.1016/j.copbio.2012.10.016

Tissue engineering on the nanoscale: Lessons from the heart

Sharon Fleischer, Tal Dvir

Research output: Contribution to journal › Review article › peer-review

82 Scopus citations

Abstract

Recognizing the limitations of biomaterials for engineering complex tissues and the desire for closer recapitulation of the natural matrix have led tissue engineers to seek new technologies for fabricating 3-dimensional (3D) cellular microenvironments. In this review, through examples from cardiac tissue engineering, we describe the nanoscale hallmarks of the extracellular matrix that tissue engineers strive to mimic. Furthermore, we discuss the use of inorganic nanoparticles and nanodevices for improving and monitoring the performance of engineered tissues. Finally, we offer our opinion on the main challenges and prospects of applying nanotechnology in tissue engineering.

Original language	English
Pages (from-to)	664-671
Number of pages	8
Journal	Current Opinion in Biotechnology
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.copbio.2012.10.016
State	Published - 1 Aug 2013
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

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10.1016/j.copbio.2012.10.016

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Tissue engineering on the nanoscale: Lessons from the heart

Abstract

ASJC Scopus subject areas

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