Abstract
Titanium tetrafluoride can efficiently be used for strereoselective synthesis of 4-fluorotetrahydropyrans via Prins cyclization in good yields. The method is general and can be used for aldehydes as well as ketones.
Original language | English |
---|---|
Pages (from-to) | 320-324 |
Number of pages | 5 |
Journal | Journal of Fluorine Chemistry |
Volume | 131 |
Issue number | 3 |
DOIs | |
State | Published - 1 Mar 2010 |
Externally published | Yes |
Keywords
- Fluorinating agent
- Lewis acid
- Prins cyclization
- Tetrahydropyran
- Titanium tetrafluoride
ASJC Scopus subject areas
- Biochemistry
- Environmental Chemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry