Titanium tetrafluoride: An efficient Lewis acid and fluorinating agent for stereoselective synthesis of 4-fluorotetrahydropyran

S. Bondalapati, U. C. Reddy, D. S. Kundu, Anil K. Saikia

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Titanium tetrafluoride can efficiently be used for strereoselective synthesis of 4-fluorotetrahydropyrans via Prins cyclization in good yields. The method is general and can be used for aldehydes as well as ketones.

Original languageEnglish
Pages (from-to)320-324
Number of pages5
JournalJournal of Fluorine Chemistry
Volume131
Issue number3
DOIs
StatePublished - 1 Mar 2010
Externally publishedYes

Keywords

  • Fluorinating agent
  • Lewis acid
  • Prins cyclization
  • Tetrahydropyran
  • Titanium tetrafluoride

ASJC Scopus subject areas

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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