Topical treatment of persistent cutaneous leishmaniasis with ethanolic lipid amphotericin B

Alex Zvulunov, Emanuala Cagnano, Shoshana Frankenburg, Yehezkel Barenholz, Daniel Vardy

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

A 1.5-year-old infant was referred because of spreading skin lesions diagnosed earlier as cutaneous leishmaniasis that did not respond to repeated courses with paromomycin-containing ointment. After consideration of the alternative therapeutic options, the infant was treated with topical colloidal solution of amphotericin B for 3 weeks. This mode of therapy resulted in resolution of the skin lesions. No local or systemic side effects were observed. There were no signs of recurrence 3 months after cessation of the treatment.

Original languageEnglish
Pages (from-to)567-569
Number of pages3
JournalPediatric Infectious Disease Journal
Volume22
Issue number6
DOIs
StatePublished - 1 Jun 2003

Keywords

  • Amphotericin B
  • Cutaneous leishmaniasis
  • Topical application

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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