TY - JOUR
T1 - Trans- and cis-1,3,5,7-Tetraazadecalin (TAD). A new and strong binding mode in cis-TAD chelates of heavy metal ions
AU - Reany, Ofer
AU - Grabarnik, Mikhail
AU - Goldberg, Israel
AU - Abramson, Sarah
AU - Star, Alexander
AU - Fuchs, Benzion
N1 - Funding Information:
This work was supported in part by grants from the Israel Science Foundation, the Ministry of Science and the Ministry of Absorption (to M. G.). The invaluable help of Prof. E. Eisner with the electrochemical methods and the skillful assistance of Ms. Zafra Stein with the X-ray measurements are gratefully acknowledged.
PY - 1997/11/17
Y1 - 1997/11/17
N2 - trans- and cis-1,3,5,7-tetraaradecalin (TAD) (2 and 3) were isolated and structurally characterized (VT-NMR). One of the cis-TAD derivatives intended to act as 'cores' of new host systems, 2,6-dihydroxymethyl)-cis-TAD (5), gave heavy metal ion (Cd(II), Pb(II), etc.) complexes with remarkably high binding constants, as measured by polarography. X-ray analyses of the Cd(II) (7a) and Pb(II) (7b) complexes revealed a new, unique binding mode.
AB - trans- and cis-1,3,5,7-tetraaradecalin (TAD) (2 and 3) were isolated and structurally characterized (VT-NMR). One of the cis-TAD derivatives intended to act as 'cores' of new host systems, 2,6-dihydroxymethyl)-cis-TAD (5), gave heavy metal ion (Cd(II), Pb(II), etc.) complexes with remarkably high binding constants, as measured by polarography. X-ray analyses of the Cd(II) (7a) and Pb(II) (7b) complexes revealed a new, unique binding mode.
UR - http://www.scopus.com/inward/record.url?scp=0030727425&partnerID=8YFLogxK
U2 - 10.1016/S0040-4039(97)10111-3
DO - 10.1016/S0040-4039(97)10111-3
M3 - Article
AN - SCOPUS:0030727425
SN - 0040-4039
VL - 38
SP - 8073
EP - 8076
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 46
ER -