Transcatheter Tricuspid Valve Device Landscape

Tricuspid regurgitation (TR) is an exceeding prevalent valve disease. Severe TR is associated with adverse prognosis. Currently, there is no effective medical treatment for severe TR and surgery for severe TR is associated with high in-hospital mortality. Both transcatheter valve replacement and valve repair have emerged as feasible and effective interventions for severe TR. Transcatheter valve repair techniques can broadly be grouped in two categories, leaflet-directed therapies and annulus-reshaping therapies. Leaflet-directed therapies are based on edge-to-edge leaflet approximation and currently constitute the majority of the outcomes data available. Alternatively, annular-reshaping therapies are aiming at the reduction of tricuspid annulus diameter. Transcatheter tricuspid valve replacement has the advantage of allowing a complete elimination of TR and can be performed relatively independent of tricuspid annulus morphology. This chapter reviews the current transcatheter tricuspid valve device landscape.