Transcranial magnetic stimulation in an amphetamine hyperactivity model of mania

Alona Shaldivin; Alexander Kaptsan; Robert H. Belmaker; Haim Einat; Nimrod Grisaru

doi:10.1034/j.1399-5618.2001.030104.x

Transcranial magnetic stimulation in an amphetamine hyperactivity model of mania

Alona Shaldivin, Alexander Kaptsan, Robert H. Belmaker, Haim Einat, Nimrod Grisaru

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Objectives: Transcranial magnetic stimulation (TMS) of the brain has been reported to have therapeutic effects in mania, as well as depression. TMS has previously been reported to have effects similar to those of electroconvulsive shock in rat models of depression. Methods: We, therefore, studied TMS in amphetamine-induced hyperactivity as a rat model of mania. Results: While two and seven daily TMS sessions significantly reduced activity after amphetamine, twice-daily TMS for 7 days enhanced activity after amphetamine. Conclusions: The results suggest that TMS treatment to rats interacts with the effects of amphetamine; the specific effects may be dependent on the schedule of treatment.

Original language	English
Pages (from-to)	30-34
Number of pages	5
Journal	Bipolar Disorders
Volume	3
Issue number	1
DOIs	https://doi.org/10.1034/j.1399-5618.2001.030104.x
State	Published - 28 Mar 2001

Keywords

Activity
Amphetamine
ECS
Mania
Rats
TMS

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

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10.1034/j.1399-5618.2001.030104.x

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AU - Grisaru, Nimrod

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Transcranial magnetic stimulation in an amphetamine hyperactivity model of mania

Abstract

Keywords

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