Transcranial magnetic stimulation induces alterations in brain monoamines

D. Ben-Shachar, R. H. Belmaker, N. Grisaru, E. Klein

    Research output: Contribution to journalArticlepeer-review

    170 Scopus citations

    Abstract

    Transcranial magnetic stimulation has been suggested as a possible therapeutic tool in depression. In behavioral models of depression, magnetic stimulation induced similar effects to those of electroconvulsive shock. This study demonstrates the effect of a single session of rapid TMS on tissue monoamines in rat brain. Alterations in monoamines were selective and specific in relation to brain areas and type of monoamine. The results imply on a biochemical basis to the suggested ECT-like treatment potential of TMS.

    Original languageEnglish
    Pages (from-to)191-197
    Number of pages7
    JournalJournal of Neural Transmission
    Volume104
    Issue number2-3
    DOIs
    StatePublished - 1 Jan 1997

    Keywords

    • Brain monoamines
    • Depression
    • Electroconvulsive shock (ECS)
    • Rat
    • Transcranial magnetic stimulation (TMS)

    ASJC Scopus subject areas

    • Neurology
    • Clinical Neurology
    • Psychiatry and Mental health
    • Biological Psychiatry

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