Transcriptional regulation of ceil division genes in Escherichia coli

S. J. Dewar, V. Kagan‐Zur, K. J. Begg, W. D. Donachie

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17 Scopus citations


The complete Escherichia coli ftsQ coding sequence, together with part of the ftsA coding sequence, has been cloned upstream of the lacZ open reading frame in a λ‐vector (λJFL100). Cells which are lysogenic for λJFL100 transcribe the cloned lacZ from promoter(s) within the ftsQ and ftsA sequences. The level of β‐galactosidase produced is dependent on growth rate (and/or cell size) and Is derepressed in an ftsA‐deficient mutant. Transcription during the cell cycle is restricted to the time of cell division.

Original languageEnglish
Pages (from-to)1371-1377
Number of pages7
JournalMolecular Microbiology
Issue number10
StatePublished - 1 Jan 1989
Externally publishedYes


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