Transcriptional regulation of ceil division genes in Escherichia coli

S. J. Dewar, V. Kagan‐Zur, K. J. Begg, W. D. Donachie

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations


    The complete Escherichia coli ftsQ coding sequence, together with part of the ftsA coding sequence, has been cloned upstream of the lacZ open reading frame in a λ‐vector (λJFL100). Cells which are lysogenic for λJFL100 transcribe the cloned lacZ from promoter(s) within the ftsQ and ftsA sequences. The level of β‐galactosidase produced is dependent on growth rate (and/or cell size) and Is derepressed in an ftsA‐deficient mutant. Transcription during the cell cycle is restricted to the time of cell division.

    Original languageEnglish GB
    Pages (from-to)1371-1377
    Number of pages7
    JournalMolecular Microbiology
    Issue number10
    StatePublished - 1 Jan 1989

    ASJC Scopus subject areas

    • Microbiology
    • Molecular Biology


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