Transient effect on mannitol on cerebral blood flow following brain injury.

E. Shalmon; E. Reichenthal; T. Kaspi

doi:10.1007/978-3-7091-9115-6_39

Transient effect on mannitol on cerebral blood flow following brain injury.

E. Shalmon, E. Reichenthal, T. Kaspi

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Abstract

CBF and ICP were measured in cats following cerebral cold injury and mannitol infusion. Mannitol was found to reduce the intracranial hypertension caused by the injury. The restoration of CBF and ICP was of short duration and was followed by a reduction of CBF and elevation of ICP. A repeated restoration of CBF by a second dose of mannitol was followed by a more severe impairment of CBF. The prolonged beneficial effect of mannitol on CBF after brain injury has to be reassessed.

Original language	English
Pages (from-to)	116-117
Number of pages	2
Journal	Acta Neurochirurgica, Supplement
Volume	51
DOIs	https://doi.org/10.1007/978-3-7091-9115-6_39
State	Published - 1 Jan 1990
Externally published	Yes

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title = "Transient effect on mannitol on cerebral blood flow following brain injury.",

abstract = "CBF and ICP were measured in cats following cerebral cold injury and mannitol infusion. Mannitol was found to reduce the intracranial hypertension caused by the injury. The restoration of CBF and ICP was of short duration and was followed by a reduction of CBF and elevation of ICP. A repeated restoration of CBF by a second dose of mannitol was followed by a more severe impairment of CBF. The prolonged beneficial effect of mannitol on CBF after brain injury has to be reassessed.",

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AU - Kaspi, T.

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N2 - CBF and ICP were measured in cats following cerebral cold injury and mannitol infusion. Mannitol was found to reduce the intracranial hypertension caused by the injury. The restoration of CBF and ICP was of short duration and was followed by a reduction of CBF and elevation of ICP. A repeated restoration of CBF by a second dose of mannitol was followed by a more severe impairment of CBF. The prolonged beneficial effect of mannitol on CBF after brain injury has to be reassessed.

AB - CBF and ICP were measured in cats following cerebral cold injury and mannitol infusion. Mannitol was found to reduce the intracranial hypertension caused by the injury. The restoration of CBF and ICP was of short duration and was followed by a reduction of CBF and elevation of ICP. A repeated restoration of CBF by a second dose of mannitol was followed by a more severe impairment of CBF. The prolonged beneficial effect of mannitol on CBF after brain injury has to be reassessed.

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JO - Acta Neurochirurgica, Supplement

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ER -

Transient effect on mannitol on cerebral blood flow following brain injury.

Abstract

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