@article{f16558538fc54b79ae9bc49021d935d4,
title = "Transient enhanced cell division by blocking DNA synthesis in Escherichia coli",
abstract = "Duplication of the bacterial nucleoid is necessary for cell division hence specific arrest of DNA replication inhibits divisions culminating in filamentation, nucleoid dispersion and appearance of a-nucleated cells. It is demonstrated here that during the first 10 min however, Escherichia coli enhanced residual divisions: the proportion of constricted cells doubled (to 40%), nucle-oids contracted and cells remodelled dimensions: length decreased and width increased. The preliminary data provides further support to the existence of temporal and spatial couplings between the nucleoid/replisome and the sacculus/divisome, and is consistent with the idea that bacillary bacteria modulate width during the division process exclusively.",
keywords = "Cell division and dimensions, DNA replication, Nucleoid morphology",
author = "Mart{\'i}n, {Carmen Mata} and Arieh Zaritsky and Itzhak Fishov and Guzm{\'a}n, {Elena C.}",
note = "Funding Information: E.G.C. acknowledges Sociedad Espa{\~n}ola de Gen{\'e}tica (SEG) for a Short-Term Fellowship and C.M.M. acknowledges the FPI studentship from the Junta de Extremadura and an EMBO Short-Term Fellowship. This work was partially supported by grant GRU15065 from the Junta de Extremadura to ECG, the United States – Israel Binational Science Foundation (No. 2017004) to A.Z. and the Israel Science Foundation to I.F. Funding Information: information E.G.C. acknowledges Sociedad Espa?ola de Gen?tica (SEG) for a Short-Term Fellowship and C.M.M. acknowledges the FPI studentship from the Junta de Extremadura and an EMBO Short-Term Fellowship. This work was partially supported by grant GRU15065 from the Junta de Extremadura to ECG, the United States ? Israel Binational Science Foundation (No. 2017004) to A.Z. and the Israel Science Foundation to I.F. Acknowledgements We are indebted to Alfonso Jim?nez-S?nchez for help with the cell-cycle data analysis, and Sharon Vanounou, Tziona Elkayam and Mario Feingold at BGU for help. Publisher Copyright: {\textcopyright} 2020 The Authors.",
year = "2020",
month = jan,
day = "1",
doi = "10.1099/mic.0.000888",
language = "English",
volume = "166",
pages = "516--521",
journal = "Microbiology (United Kingdom)",
issn = "1350-0872",
publisher = "Microbiology Society",
number = "6",
}