TY - JOUR
T1 - Transient versus stable nature of fear of falling over 24 months in community-older persons with falls– data of the EU SCOPE project on Kidney function
AU - SCOPE investigators
AU - Freiberger, Ellen
AU - Fabbietti, Paolo
AU - Corsonello, Andrea
AU - Lattanzio, Fabrizia
AU - Artzi-Medvedik, Rada
AU - Kob, Robert
AU - Melzer, Itshak
AU - Wirnsberger, Gerhard
AU - Roller-Wirnsberger, Regina
AU - Mattace-Raso, Francesco
AU - Tap, Lisanne
AU - Kostka, Tomasz
AU - Guligowska, Agnieszka
AU - Formiga, Francesc
AU - Moreno-González, Rafael
AU - Gil, Pedro
AU - Martínez, Sara Laínez
AU - Bekmann, Andreas
AU - Weingart, Christian
AU - Sieber, Cornel
AU - Ärnlöv, Johan
AU - Carlsson, Axel
AU - Britting, Sabine
N1 - Funding Information:
Open Access funding enabled and organized by Projekt DEAL. SCOPE study and publication costs are funded by the European Union Horizon 2020 program, under the Grant Agreement n° 634869. Funding body had no role in the design of the study and collection, analysis, and interpretation of data, writing the manuscript and in the decision to publish the results.
Funding Information:
We thank the participants for their time and motivation in our study. SCOPE consortium Fabrizia Lattanzio2Paolo Fabbietti2Andrea Corsonello2Gerhard Wirnsberger6Regina Roller-Wirnsberger6Francesco Mattace-Raso7Lisanne Tap7Tomasz Kostka8Agnieszka Guligowska8Rada Artzi-Medvedik3,4Itshak Melzer5Francesc Formiga9Rafael Moreno-González9Pedro Gil10Sara Laínez Martínez10Ellen Freiberger1Robert Kob1Sabine Britting1Andreas Bekmann11Christian Weingart11Cornel Sieber1,12Johan Ärnlöv13Axel Carlsson131Department of Internal Medicine-Geriatrics, Institute for Biomedicine of Aging (IBA), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.2Italian National Research Center on Aging (IRCCS INRCA), Ancona, Fermo and Cosenza, Italy.3Department of Nursing, Recanati School for Community Health Professions at the faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.4Maccabi Health Services, Israel; and Department of Nursing, Recanati School for Community Health Professions at the faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.5Department of Physical Therapy, Recanati School for Community Health Professions at the faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.6Department of Internal Medicine, Medical University of Graz, Austria.7Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands.8Department of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, Poland.9Geriatric Unit, Internal Medicine Department and Nephrology Department, Hospital Universitari de Bellvitge, Institut d’Investigació Biomèdica de Bellvitge—IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.10Department of Geriatric Medicine, Hospital Clínico San Carlos, Madrid, Spain.11Department of General Internal Medicine and Geriatrics, Institute for Biomedicine of Aging, Krankenhaus Barmherzige Brüder, Friedrich-Alexander-Universität Erlangen-Nürnberg, Regensburg, Germany.12Department of Medicine, Kantonsspital Winterthur, Winterthur, Switzerland.13Department of Medical Sciences, Uppsala University, Sweden. A full list of members and their affiliations appears in the Supplementary Information.
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12/1
Y1 - 2022/12/1
N2 - Background: Fear of falling (FoF) is an important risk factor for falls among older people. The objectives of our investigations were: a.) to present characteristics of older community-dwelling (CD) fallers with persistent or transient FoF (P-FoF or T-FoF) over 12 months, and b.) to investigate clinical predictors of P-FoF and T-FoF and c.) to explore differences between P-FoF and T-FoF. Methods: Our series consisted of 389 older people reporting a fall or injurious fall at baseline and during 24 months follow-up participating in a multicenter prospective study. T-FoF was defined as participants reported “not at all” at baseline and “somewhat/fairly/very concerned” at follow-up, or “not at all” at follow-up, and “somewhat/fairly/very concerned” at baseline, and P-FoF was defined as participants answered “somewhat/fairly/very concerned” in both assessments at baseline and at follow-up. The association between risk factors and T-FoF or P-FoF was investigated by logistic regression analysis. Results: The mean age of fallers in our sample was 79.0 years (SD 6.0), and 54.2% were females. Out of 389 older adults with a fall history at baseline, 83 participants (21.3%) did not report any FoF over time, P-FoF and T-FoF were observed in 42.7% and 35.9% of participants, respectively. After adjusting for potential confounders (e.g. age, gender), osteoporosis (OR = 2.04, 95%CI = 1.03–4.05) and impaired physical performance (OR = 2.38, 95%CI = 1.12–5.03) were significant predictors of T-FoF vs No-FoF. Osteoporosis (OR = 2.68, 95%CI = 1.31–5.48), depressive symptoms (OR = 3.54, 95%CI = 1.23–10.1) and living alone (OR = 2.44, 95%CI = 1.17–5.06) were significantly associated with P-FoF vs No-FoF. When comparing T-FoF and P-FoF, female gender (OR = 1.95, 95%CI = 1.16–3.27), BMI (OR = 1.08, 95%CI = 1.02–1.14), overall comorbidity (OR = 1.07, 95%CI = 1.02–1.13) and depression (OR = 2.55, 95%CI = 1.33–4.88) were significant predictors of P-FoF. Conclusions: T-FoF and P-FoF may be predicted by different sets of risk factors among older fallers. Thus, fallers should be screened for FoF especially when carrying specific risk factors, including female gender, osteoporosis, depression, living alone, impaired physical performance, BMI, comorbidity. These findings may be helpful in designing tailored intervention to blunt the risks related to consequence of FoF among older people experiencing falls. Trial registration: The SCOPE study was registered prospectively at clinicaltrials.gov (NCT02691546; 25/02/2016).
AB - Background: Fear of falling (FoF) is an important risk factor for falls among older people. The objectives of our investigations were: a.) to present characteristics of older community-dwelling (CD) fallers with persistent or transient FoF (P-FoF or T-FoF) over 12 months, and b.) to investigate clinical predictors of P-FoF and T-FoF and c.) to explore differences between P-FoF and T-FoF. Methods: Our series consisted of 389 older people reporting a fall or injurious fall at baseline and during 24 months follow-up participating in a multicenter prospective study. T-FoF was defined as participants reported “not at all” at baseline and “somewhat/fairly/very concerned” at follow-up, or “not at all” at follow-up, and “somewhat/fairly/very concerned” at baseline, and P-FoF was defined as participants answered “somewhat/fairly/very concerned” in both assessments at baseline and at follow-up. The association between risk factors and T-FoF or P-FoF was investigated by logistic regression analysis. Results: The mean age of fallers in our sample was 79.0 years (SD 6.0), and 54.2% were females. Out of 389 older adults with a fall history at baseline, 83 participants (21.3%) did not report any FoF over time, P-FoF and T-FoF were observed in 42.7% and 35.9% of participants, respectively. After adjusting for potential confounders (e.g. age, gender), osteoporosis (OR = 2.04, 95%CI = 1.03–4.05) and impaired physical performance (OR = 2.38, 95%CI = 1.12–5.03) were significant predictors of T-FoF vs No-FoF. Osteoporosis (OR = 2.68, 95%CI = 1.31–5.48), depressive symptoms (OR = 3.54, 95%CI = 1.23–10.1) and living alone (OR = 2.44, 95%CI = 1.17–5.06) were significantly associated with P-FoF vs No-FoF. When comparing T-FoF and P-FoF, female gender (OR = 1.95, 95%CI = 1.16–3.27), BMI (OR = 1.08, 95%CI = 1.02–1.14), overall comorbidity (OR = 1.07, 95%CI = 1.02–1.13) and depression (OR = 2.55, 95%CI = 1.33–4.88) were significant predictors of P-FoF. Conclusions: T-FoF and P-FoF may be predicted by different sets of risk factors among older fallers. Thus, fallers should be screened for FoF especially when carrying specific risk factors, including female gender, osteoporosis, depression, living alone, impaired physical performance, BMI, comorbidity. These findings may be helpful in designing tailored intervention to blunt the risks related to consequence of FoF among older people experiencing falls. Trial registration: The SCOPE study was registered prospectively at clinicaltrials.gov (NCT02691546; 25/02/2016).
KW - Fallers
KW - Falls
KW - Fear of falling
KW - Injurious falls
KW - Older people
KW - Osteoporosis
KW - Physical function
UR - http://www.scopus.com/inward/record.url?scp=85136360012&partnerID=8YFLogxK
U2 - 10.1186/s12877-022-03357-0
DO - 10.1186/s12877-022-03357-0
M3 - Article
C2 - 35999522
AN - SCOPUS:85136360012
SN - 1471-2318
VL - 22
JO - BMC Geriatrics
JF - BMC Geriatrics
IS - 1
M1 - 698
ER -