Transport of αaminoisobutyric acid into rat parotid after x-irradiation

Lipa Bodner

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Rat parotid gland exposed to 20 Gy X-irradiation exhibits functional alteration 3 days after exposure. The flow rate of saliva and the uptake of αaminoisobutyric acid by the gland was reduced to 50 per cent of values for the control nonirradiated glands. When the same gland was studied in an in vitro system it functioned normally. K+ release and αaminoisobutyric acid uptake by the irradiated dispersed acinar cells was comparable to the control. Transport alteration from the circulatory system into the parotid gland may cause the initial radiation-induced damage.

Original languageEnglish
Pages (from-to)653-660
Number of pages8
JournalInternational Journal of Radiation Biology
Volume55
Issue number4
DOIs
StatePublished - 1 Jan 1989
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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