Treatment of multiple miliary osteoma cutis of the face with local application of tretinoin (all-trans-retinoic acid): A case report and review of the literature

A. D. Cohen, T. Chetov, E. Cagnano, S. Naimer, D. A. Vardy

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

BACKGROUND: Multiple miliary osteoma cutis of the face represents primary extra-skeletal bone formation that arises within the skin of the face. METHODS: A 60-year-old woman with multiple miliary osteoma cutis of the face was treated by application of 0.05% tretinoin (all-trans-retinoic acid) cream nightly. RESULTS: After 3 months of therapy there were fewer papules and a decrease in size of remaining lesions. In a literature search, it was found that local application of tretinoin was successful and achieved a decrease in the number of papules over the face in all patients with multiple miliary osteoma cutis of the face; however, the length of time to achieve response varied from a few weeks to 6 months. CONCLUSION: It is suggested that local application of tretinoin cream should be considered in the therapy of multiple miliary osteoma cutis of the face, particularly when the lesions are small and superficial.

Original languageEnglish
Pages (from-to)171-173
Number of pages3
JournalJournal of Dermatological Treatment
Volume12
Issue number3
DOIs
StatePublished - 17 Dec 2001
Externally publishedYes

Keywords

  • Multiple miliary osteoma cutis of the face
  • Review
  • Treatment
  • Tretinoin

ASJC Scopus subject areas

  • Dermatology

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