Tuning hydrogel properties and function using substituent effects

Richie E. Kohman; Chaenyung Cha; Steven C. Zimmerman; Hyunjoon Kong

doi:10.1039/c001548b

Tuning hydrogel properties and function using substituent effects

Richie E. Kohman, Chaenyung Cha, Steven C. Zimmerman, Hyunjoon Kong

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.

Original language	English
Pages (from-to)	2150-2152
Number of pages	3
Journal	Soft Matter
Volume	6
Issue number	10
DOIs	https://doi.org/10.1039/c001548b
State	Published - 21 May 2010
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
Condensed Matter Physics

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10.1039/c001548b

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abstract = "The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.",

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AU - Cha, Chaenyung

AU - Zimmerman, Steven C.

AU - Kong, Hyunjoon

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AB - The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.

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Tuning hydrogel properties and function using substituent effects

Abstract

ASJC Scopus subject areas

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