Tuning hydrogel properties and function using substituent effects

Richie E. Kohman; Chaenyung Cha; Steven C. Zimmerman; Hyunjoon Kong

doi:10.1039/c001548b

Tuning hydrogel properties and function using substituent effects

Richie E. Kohman
, Chaenyung Cha
, Steven C. Zimmerman
, Hyunjoon Kong

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.

Original language	English
Pages (from-to)	2150-2152
Number of pages	3
Journal	Soft Matter
Volume	6
Issue number	10
DOIs	https://doi.org/10.1039/c001548b
State	Published - 21 May 2010
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
Condensed Matter Physics

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10.1039/c001548b

Cite this

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title = "Tuning hydrogel properties and function using substituent effects",

abstract = "The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.",

author = "Kohman, \{Richie E.\} and Chaenyung Cha and Zimmerman, \{Steven C.\} and Hyunjoon Kong",

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AU - Kohman, Richie E.

AU - Cha, Chaenyung

AU - Zimmerman, Steven C.

AU - Kong, Hyunjoon

PY - 2010/5/21

Y1 - 2010/5/21

N2 - The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.

AB - The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-triazaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.

UR - https://www.scopus.com/pages/publications/77952346699

U2 - 10.1039/c001548b

DO - 10.1039/c001548b

M3 - Article

AN - SCOPUS:77952346699

SN - 1744-683X

VL - 6

SP - 2150

EP - 2152

JO - Soft Matter

JF - Soft Matter

IS - 10

ER -

Tuning hydrogel properties and function using substituent effects

Abstract

ASJC Scopus subject areas

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