TY - JOUR
T1 - Two-position supine/prone myocardial perfusion SPECT (MPS) imaging improves visual inter-observer correlation and agreement
AU - Arsanjani, Reza
AU - Hayes, Sean W.
AU - Fish, Mathews
AU - Shalev, Aryeh
AU - Nakanishi, Rine
AU - Thomson, Louise E.J.
AU - Friedman, John D.
AU - Germano, Guido
AU - Berman, Daniel S.
AU - Slomka, Piotr
N1 - Funding Information:
This research was supported in part by Grants R01HL089765 from the National Heart, Lung, and Blood Institute/National Institutes of Health (NHLBI/NIH). We would like to thank Dr. Caroline Kilian and Arpine Oganyan for proof reading the text, Mr. Jim Gerlach for quality controls of the data, and Ms. Heidi Gransar for the statistical analysis.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Objectives. We aimed to compare the inter-observer agreement between two experienced readers using supine vs combined supine/prone myocardial perfusion SPECT (MPS) in a large population. Methods. 1,181 consecutive patients without known coronary artery disease (CAD) undergoing rest 201Tl/stress 99mTc-sestamibi MPS studies were evaluated. Visual reads were performed in two consecutive steps, with readers scoring the stress supine perfusion images during step 1 and rescoring the images using both supine/prone data during step 2. Visual summed stress scores (SSS) of two readers including regional scores in different vascular territories were compared. Results. The specificity for both readers improved using combined supine/prone imaging (reader 1: 92% vs 86% [P = .0002], reader 2: 88% vs 72% [P < .0001]). The inter-observer correlation for SSS (0.90 vs 0.84, P < .0001) and inter-observer agreement for combined supine/prone reading (bias = 1.0, 95% confidence interval (CI) 0.9-1.2 vs bias = 3.1, 95% CI 2.8-3.4, P < .0001) were significantly better as compared to supine-only reading. The overall correlation between SSS scores for two readers improved with supine/prone imaging for both genders, as well as in the left anterior descending and right coronary territories. Conclusion. The inter-observer correlation and agreement significantly improve using two-position supine/prone vs supine-only imaging.
AB - Objectives. We aimed to compare the inter-observer agreement between two experienced readers using supine vs combined supine/prone myocardial perfusion SPECT (MPS) in a large population. Methods. 1,181 consecutive patients without known coronary artery disease (CAD) undergoing rest 201Tl/stress 99mTc-sestamibi MPS studies were evaluated. Visual reads were performed in two consecutive steps, with readers scoring the stress supine perfusion images during step 1 and rescoring the images using both supine/prone data during step 2. Visual summed stress scores (SSS) of two readers including regional scores in different vascular territories were compared. Results. The specificity for both readers improved using combined supine/prone imaging (reader 1: 92% vs 86% [P = .0002], reader 2: 88% vs 72% [P < .0001]). The inter-observer correlation for SSS (0.90 vs 0.84, P < .0001) and inter-observer agreement for combined supine/prone reading (bias = 1.0, 95% confidence interval (CI) 0.9-1.2 vs bias = 3.1, 95% CI 2.8-3.4, P < .0001) were significantly better as compared to supine-only reading. The overall correlation between SSS scores for two readers improved with supine/prone imaging for both genders, as well as in the left anterior descending and right coronary territories. Conclusion. The inter-observer correlation and agreement significantly improve using two-position supine/prone vs supine-only imaging.
KW - Inter-observer agreement
KW - coronary artery disease
KW - myocardial perfusion SPECT
KW - supine-prone SPECT
KW - visual summed stress score
UR - http://www.scopus.com/inward/record.url?scp=84905113368&partnerID=8YFLogxK
U2 - 10.1007/s12350-014-9895-3
DO - 10.1007/s12350-014-9895-3
M3 - Article
AN - SCOPUS:84905113368
SN - 1071-3581
VL - 21
SP - 703
EP - 711
JO - Journal of Nuclear Cardiology
JF - Journal of Nuclear Cardiology
IS - 4
ER -
