Two sequential outbreaks of rotavirus gastroenteritis: Evidence for symptomatic and asymptomatic reinfections

Maureen G. Friedman, Aharon Galil, Batia Sarov, Miriam Margalith, Gila Katzir, Karen Midthun, Koki Taniguchi, Shozo Urasawa, Albert Z. Kapikian, Robert Edelman, Israel Sarov

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

In two sequential outbreaks of rotavirus gastroenteritis that occurred in a kibbutz in southern Israel (the Negev), 32 persons (9% of the population) were ill in the first and 45 (13% of the population) in the second. Excretion of virus, changes in titers of rotavirus-specific serum IgG, or both implicated rotavirus in 72% of the illnesses in outbreak 1 and in 56% of the illnesses in outbreak 2. In both outbreaks the age-specific morbidity rate decreased with increasing age. Half (six of 12) of the children six to 27 months of age who were ill with rotavirus in outbreak 1 were ill with rotavirus again in outbreak 2, whereas two were asymptomatically infected; older children who were ill in outbreak 1 were not ill in outbreak 2. Serotype determination by enzyme-linked immunosorbent assay using monoclonal antibodies to VP7 implicated a serotype 3 virus in outbreak 1 and a serotype 1 virus in outbreak 2.

Original languageEnglish
Pages (from-to)814-822
Number of pages9
JournalJournal of Infectious Diseases
Volume158
Issue number4
DOIs
StatePublished - 1 Jan 1988
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Two sequential outbreaks of rotavirus gastroenteritis: Evidence for symptomatic and asymptomatic reinfections'. Together they form a unique fingerprint.

Cite this