TY - JOUR
T1 - Two sequential outbreaks of rotavirus gastroenteritis
T2 - Evidence for symptomatic and asymptomatic reinfections
AU - Friedman, Maureen G.
AU - Galil, Aharon
AU - Sarov, Batia
AU - Margalith, Miriam
AU - Katzir, Gila
AU - Midthun, Karen
AU - Taniguchi, Koki
AU - Urasawa, Shozo
AU - Kapikian, Albert Z.
AU - Edelman, Robert
AU - Sarov, Israel
PY - 1988/1/1
Y1 - 1988/1/1
N2 - In two sequential outbreaks of rotavirus gastroenteritis that occurred in a kibbutz in southern Israel (the Negev), 32 persons (9% of the population) were ill in the first and 45 (13% of the population) in the second. Excretion of virus, changes in titers of rotavirus-specific serum IgG, or both implicated rotavirus in 72% of the illnesses in outbreak 1 and in 56% of the illnesses in outbreak 2. In both outbreaks the age-specific morbidity rate decreased with increasing age. Half (six of 12) of the children six to 27 months of age who were ill with rotavirus in outbreak 1 were ill with rotavirus again in outbreak 2, whereas two were asymptomatically infected; older children who were ill in outbreak 1 were not ill in outbreak 2. Serotype determination by enzyme-linked immunosorbent assay using monoclonal antibodies to VP7 implicated a serotype 3 virus in outbreak 1 and a serotype 1 virus in outbreak 2.
AB - In two sequential outbreaks of rotavirus gastroenteritis that occurred in a kibbutz in southern Israel (the Negev), 32 persons (9% of the population) were ill in the first and 45 (13% of the population) in the second. Excretion of virus, changes in titers of rotavirus-specific serum IgG, or both implicated rotavirus in 72% of the illnesses in outbreak 1 and in 56% of the illnesses in outbreak 2. In both outbreaks the age-specific morbidity rate decreased with increasing age. Half (six of 12) of the children six to 27 months of age who were ill with rotavirus in outbreak 1 were ill with rotavirus again in outbreak 2, whereas two were asymptomatically infected; older children who were ill in outbreak 1 were not ill in outbreak 2. Serotype determination by enzyme-linked immunosorbent assay using monoclonal antibodies to VP7 implicated a serotype 3 virus in outbreak 1 and a serotype 1 virus in outbreak 2.
UR - http://www.scopus.com/inward/record.url?scp=0023683514&partnerID=8YFLogxK
U2 - 10.1093/infdis/158.4.814
DO - 10.1093/infdis/158.4.814
M3 - Article
C2 - 2844919
AN - SCOPUS:0023683514
SN - 0022-1899
VL - 158
SP - 814
EP - 822
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 4
ER -
