TY - JOUR
T1 - Ultrashort gonadotropin-releasing hormone agonist combined with flexible multidose gonadotropin-releasing hormone antagonist for poor responders in in vitro fertilization/embryo transfer programs
AU - Orvieto, Raoul
AU - Kruchkovich, Jenny
AU - Rabinson, Jacob
AU - Zohav, Efraim
AU - Anteby, Eyal Y.
AU - Meltcer, Simion
PY - 2008/7/1
Y1 - 2008/7/1
N2 - To evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in poor responders, we compared the stimulation characteristics of 21 cycles, which included the ultrashort gonadotropin-releasing hormone (GnRH) agonist combined with the flexible multidose GnRH antagonist, to the patients' previous failed in vitro fertilization attempts. The use of an ultrashort GnRH-agonist/GnRH-antagonist COH protocol resulted in a statistically significantly greater number of follicles larger than 14 mm on the day of hCG administration, a higher number of oocytes retrieved and embryos transferred, and a reasonable clinical pregnancy rate (14.3%).
AB - To evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in poor responders, we compared the stimulation characteristics of 21 cycles, which included the ultrashort gonadotropin-releasing hormone (GnRH) agonist combined with the flexible multidose GnRH antagonist, to the patients' previous failed in vitro fertilization attempts. The use of an ultrashort GnRH-agonist/GnRH-antagonist COH protocol resulted in a statistically significantly greater number of follicles larger than 14 mm on the day of hCG administration, a higher number of oocytes retrieved and embryos transferred, and a reasonable clinical pregnancy rate (14.3%).
UR - http://www.scopus.com/inward/record.url?scp=45849093342&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2007.06.022
DO - 10.1016/j.fertnstert.2007.06.022
M3 - Article
C2 - 17681292
AN - SCOPUS:45849093342
SN - 0015-0282
VL - 90
SP - 228
EP - 230
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 1
ER -