Ultrasonic energy for construction of bioactive heterocycles

Omkar Kamble; Rana Chatterjee; Ramababu Dandela; Sandip Shinde

doi:10.1016/j.tet.2022.132893

Ultrasonic energy for construction of bioactive heterocycles

Omkar Kamble, Rana Chatterjee, Ramababu Dandela, Sandip Shinde

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Abstract

The ultrasonic energy has been revisited and applied for the synthesis of bioactive molecules in a short time and green method. These compounds can exhibit anticancer, antioxidant, antibacterial, antimalarial, and cytotoxic properties. Some of them are organofluorines, that are widely used as potential pharmacological agents. Significantly, the synthesis of a compound having activity against SARS-CoV-2 has also been studied in this review. The complete ultrasound-assisted synthesis is catalyzed by different chemical catalysts. Ultrasonication is a promising technique for the green synthesis, rapid approach, quantitative yield of the desired molecules and brief biological importance. Among the unconventional methods, ultrasonication has drawn attention as a promising approach for the green and rapid synthesis of biological sensitive molecules in a considerable quantity.

Original language	English
Article number	132893
Journal	Tetrahedron
Volume	120
DOIs	https://doi.org/10.1016/j.tet.2022.132893
State	Published - 13 Aug 2022
Externally published	Yes

Keywords

Green synthesis
Heterocyclic
Medicinal chemistry
Multicomponent
Organic synthesis
Ultrasonic

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tet.2022.132893

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title = "Ultrasonic energy for construction of bioactive heterocycles",

abstract = "The ultrasonic energy has been revisited and applied for the synthesis of bioactive molecules in a short time and green method. These compounds can exhibit anticancer, antioxidant, antibacterial, antimalarial, and cytotoxic properties. Some of them are organofluorines, that are widely used as potential pharmacological agents. Significantly, the synthesis of a compound having activity against SARS-CoV-2 has also been studied in this review. The complete ultrasound-assisted synthesis is catalyzed by different chemical catalysts. Ultrasonication is a promising technique for the green synthesis, rapid approach, quantitative yield of the desired molecules and brief biological importance. Among the unconventional methods, ultrasonication has drawn attention as a promising approach for the green and rapid synthesis of biological sensitive molecules in a considerable quantity.",

keywords = "Green synthesis, Heterocyclic, Medicinal chemistry, Multicomponent, Organic synthesis, Ultrasonic",

author = "Omkar Kamble and Rana Chatterjee and Ramababu Dandela and Sandip Shinde",

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year = "2022",

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doi = "10.1016/j.tet.2022.132893",

language = "English",

volume = "120",

journal = "Tetrahedron",

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T1 - Ultrasonic energy for construction of bioactive heterocycles

AU - Kamble, Omkar

AU - Chatterjee, Rana

AU - Dandela, Ramababu

AU - Shinde, Sandip

PY - 2022/8/13

Y1 - 2022/8/13

N2 - The ultrasonic energy has been revisited and applied for the synthesis of bioactive molecules in a short time and green method. These compounds can exhibit anticancer, antioxidant, antibacterial, antimalarial, and cytotoxic properties. Some of them are organofluorines, that are widely used as potential pharmacological agents. Significantly, the synthesis of a compound having activity against SARS-CoV-2 has also been studied in this review. The complete ultrasound-assisted synthesis is catalyzed by different chemical catalysts. Ultrasonication is a promising technique for the green synthesis, rapid approach, quantitative yield of the desired molecules and brief biological importance. Among the unconventional methods, ultrasonication has drawn attention as a promising approach for the green and rapid synthesis of biological sensitive molecules in a considerable quantity.

AB - The ultrasonic energy has been revisited and applied for the synthesis of bioactive molecules in a short time and green method. These compounds can exhibit anticancer, antioxidant, antibacterial, antimalarial, and cytotoxic properties. Some of them are organofluorines, that are widely used as potential pharmacological agents. Significantly, the synthesis of a compound having activity against SARS-CoV-2 has also been studied in this review. The complete ultrasound-assisted synthesis is catalyzed by different chemical catalysts. Ultrasonication is a promising technique for the green synthesis, rapid approach, quantitative yield of the desired molecules and brief biological importance. Among the unconventional methods, ultrasonication has drawn attention as a promising approach for the green and rapid synthesis of biological sensitive molecules in a considerable quantity.

KW - Green synthesis

KW - Heterocyclic

KW - Medicinal chemistry

KW - Multicomponent

KW - Organic synthesis

KW - Ultrasonic

UR - https://www.scopus.com/pages/publications/85133327115

U2 - 10.1016/j.tet.2022.132893

DO - 10.1016/j.tet.2022.132893

M3 - Review article

AN - SCOPUS:85133327115

SN - 0040-4020

VL - 120

JO - Tetrahedron

JF - Tetrahedron

M1 - 132893

ER -

Ultrasonic energy for construction of bioactive heterocycles

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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