Abstract
The effect of therapeutic range ultrasound on skin permeability was studied in vitro. Permeating molecule ionization state, pH, ultrasound duration, reversibility of the enhancement phenomenon, and skin structural alterations were evaluated. It was found that ultrasound affects the permeability of both ionized and unionized molecules. No irreversible structural alterations due to the ultrasound exposure were detected in the stratum corneum. Ultrasound enhancing mechanism was discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 147-156 |
| Number of pages | 10 |
| Journal | Journal of Biomaterials Science, Polymer Edition |
| Volume | 5 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - 1 Jan 1994 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 7 Affordable and Clean Energy
Keywords
- Skin permeability enhancers
- Transdermal drug delivery
- ultrasound
ASJC Scopus subject areas
- Biophysics
- Bioengineering
- Biomaterials
- Biomedical Engineering
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